Pathogenesis (Second Edition) (2019) Board Game

Pathogenesis (Second Edition) is a card game that was released in in 2019. It is designed by somersault1824 and features artwork by WIBAI Games. The game falls under the categories of card game, educational, and medical, making it a unique and educational gaming experience for players. With its cooperative gameplay and deck-building mechanics, Pathogenesis offers a challenging and engaging experience for 1 to 4 players.

Game Components of Pathogenesis

Starter deck of cards including pathogens and New DNA cards

Pathogen cards with genetic values and attack/defense values

Barrier cards for each of the body’s three tracts

Immune Response cards

Genetic value tokens

Active Gene Pool cards (more powerful pathogens, toxins, traits, and environment cards)

Damage counters

How To Setup Pathogenesis

To set up the game, each player starts with a starter deck containing initial pathogens and New DNA cards. The body’s three tracts are prepared with their respective barrier decks. The Active Gene Pool is set up with various cards for purchase. The Immune Response deck is also prepared, ready to be drawn from as the game progresses.

Gameplay Mechanics and Game Objective

Deck Building: Players build their decks by buying new pathogens, toxins, traits, and environment cards from the Active Gene Pool using genetic value tokens.

Attack and Defense: Players attack the body’s tracts by overcoming barrier cards and then directly damaging the body, while defending against the immune system.

Upgrading Pathogens: Players can upgrade their pathogens by replacing them with more powerful ones and attaching toxins and traits.

Game Modes: Solo, cooperative, competitive, and 2 vs. 2 team play.

Solo and Competitive: Take down one tract.

Team Play: Take down two tracts.

Cooperative: Take down all three tracts.

Objective: Cause enough damage to the body before the Immune Response deck depletes, or collect the most damage counters in competitive modes.

Player Experience

In Pathogenesis, players take on the roles of bacterial pathogens attempting to infiltrate and damage the human body. The game is scientifically grounded, with mechanics that mimic real biological processes. Players must strategically manage their deck, upgrading pathogens and leveraging special abilities to overcome the body’s defenses. The game offers a dynamic experience with varying levels of complexity and strategy, making it engaging for players who enjoy deck-building and strategic gameplay.

Pros

Scientific Accuracy: Based on real science, providing an educational element.

Multiple Game Modes: Offers versatility with solo, cooperative, competitive, and team play options.

Strategic Depth: Requires careful deck management and strategic decision-making.

Engaging Theme: Unique and interesting theme of bacterial pathogens attacking the human body.

Cons

Complex Setup: Setting up the game can be time-consuming due to the multiple components.

Steep Learning Curve: The game mechanics and strategies can be challenging for new players to grasp.

Immune Response System: The immune system mechanics can sometimes feel overwhelming or unforgiving.

Personal Thoughts on Pathogenesis

Pathogenesis is ideal for players who enjoy deck-building games and are interested in a scientifically accurate theme. It is suitable for players aged 14 and above, and it supports 1-4 players, making it a versatile addition to any board game collection. The game’s multiple modes cater to different player preferences, from solo challenges to cooperative and competitive play. However, it may not be the best fit for those looking for a simple, quick game due to its complexity and setup time.

We are supported by our audience. When you purchase through links on our site, we may earn an affiliate commission, at no extra cost for you. Learn more.